David I. Shreiber
Department of Biochem Engineering
599 Taylor Road
Piscataway, NJ 08855
CNS injury mechanics, tissue engineering, nerve and spinal cord regeneration, acupuncture, microfluidics
We are interested in understanding Central Nervous System injury, repair, and regeneration. We study the tissue and cellular biomechanics associated with traumatic injury using in vivo, in situ, and computational models. We attempt to dictate cell migration and axon regeneration by imposing spatial patterns of mechanical properties and bioactivity in collagen gels using BioMEMS. Finally, we use in vitro and computational models to investigate mechanotransduction as a mechanism underlying the response to acupuncture.