Jean Baum
Distinguished Professor
Department: Department of Chemistry
Phone: 1.8484455666
Email: mailto:baum@chem.rutgers.edu
Rutgers University
174 Frelinghuysen Rd.
Piscataway, NJ 08854
Key Words: NMR, protein folding, molecular recognition

Our research involves the development and application of nuclear magnetic resonance (NMR) spectroscopy to the study of proteins. Methods of high-resolution NMR in conjunction with computer algorithms are used to examine the dynamics and three-dimensional structures of proteins in solution.

One area of interest is to use NMR to understand the manner in which a protein folds from an unstructured state to its final compact globular structure. The study of the folding intermediates may provide a description of the pathways by which this important process occurs. A second area of interest involves protein-protein interactions and molecular recognition in proteins of medical and biological interest. The emphasis of the research is to develop novel NMR methods and apply existing techniques to mo