James S. Goydos
Department: Department of Surgery
Phone: 1.7322357593
Email: mailto:goydosjs@cinj.rutgers.edu
Robert Wood Johnson Medical School
Cancer Institute of New Jersey, , Room 3003
195 Little Albany Street
New Brunswick, NJ 08854
Key Words: Melanoma and soft tissue oncology

The goals of this project are to examine the relationship of known prognositic variables in primary melanomas and level of Grm1 expression, to perform in vivo testing of anti-glutamate therapies in melanoma xenograft models, and to determine if suppression of Grm1 signaling affects migration and invasion, uPA expression, and vasculogenic mimicry in aggressive melanoma cell lines.