The goal of my lab is to study how deficits in brain development affect cognitive function. We start from the identification of genes which cause neurodevelopmental diseases such as intellectual disability, autism spectrum disorder or brain malformations, and then use animal models (mouse and zebrafish) to recapitulate the human disease, understand pathogenesis and study the molecular mechanisms of development. We are particularly interested in intracellular signaling deficits that could be targeted for the development of novel therapies.
Program Faculty
- M. Chiara Manzini
- Associate Professor
- Department: Department of Neuroscience and Cell Biology
- Graduate Program(s): Biochemistry | Cell and Developmental Biology
- Major Research Interest(s): Disease genetics, Learning / memory, Neurological disease, Neuroscience, Signaling
- Research Techniques: Biochemistry, Cell Biology, Genetics, Proteomics, Transcriptomics
- Research Organism(s): Cell lines, Mice, Zebrafish
- Rotation Faculty
- Phone: 1.7322353245
- Email: chiara.manzini@rutgers.edu
- Rutgers Robert Wood Johnson Medical School
- Child Health Institute of New Jersey CHI, Room 3274
- 89 French Street
- New Brunswick, NJ 08901-1935
- Key Words: neurodevelopmental disease, neuromuscular disease, genetics, zebrafish
- Lab Site URL
