The first year curriculum is evenly divided between coursework and spending time in potential thesis labs (Rotations).  

In the fall semester, the core curriculum consists of an interdisciplinary foundational course coordinated with a journal-based class that teaches students to embrace the primary literature while exposing them to fundamental experimental methods and quantitative data analysis. Students enroll in Fundamentals of Molecular Biosciences, Experimental Methods in Molecular Biosciences, and Essential Skills I. (See course descriptions below.)

In the spring semester, mini courses, which span four-week blocks, focus on specific topics that take advantage of faculty expertise and research interests on campus. Mini courses give students opportunities to develop writing, speaking, presentation, modeling, or other skills as appropriate. Mini courses allow for close interaction of small groups of students with faculty engaged in cutting-edge research. Students select a total of six mini courses for the spring semester and also enroll in Essential Skills II and Ethical Scientific Conduct.

Throughout the first year, students participate in three 8 to 10-week laboratory rotations to select a thesis lab. The last rotation ends in April, and most students have joined a lab by May.  See list of current rotation faculty.

First-year students also attend the weekly Graduate Student Research Seminar to become familiar with the research carried out by upper-level students.

Examples of previously held courses and past mini course topics can be found on the Archived Courses page.

Course Descriptions

Title Course Code Credits Semester/Year

Fundamentals of Molecular Biosciences

16:695:538 6 Fall 2025

Experimental Methods in Molecular Biosciences

16:695:539 2 Fall 2025

Essential Skills I

16:695:551 1 Fall 2025, Fall 2024, Fall 2023

Essential Skills II

16:695:552 1 Spring 2026, Spring 2025, Spring 2024

Laboratory Rotations I

16:695:615 3 Fall 2025, Fall 2024, Fall 2023

Laboratory Rotations II

16:695:616 3 Spring 2026, Spring 2025, Spring 2024

Ethical Scientific Conduct

16:115:556 1 Spring 2026, Spring 2025, Spring 2024, Spring 2023, Spring 2022, Spring 2021

Progress Reports of Graduate Students in Molecular Biosciences

16:695:600 0 Spring 2026, Fall 2025, Spring 2025, Fall 2024, Spring 2024, Fall 2023

MBS Mini Courses (695)

First-year MBS Ph.D. students select a total of 6 courses mini courses for the Spring semester (2 courses per block). Block 1 course codes are 621-625; Block 2 course codes are 626-630; Block 3 course codes are 631-636. MBS Ph.D. students in their second year and beyond, or CDB or MMG Master's students, register for the number of courses as needed.

Title Course Code Credits Semester/Year

Modulating Bioelectricity for the Treatment of Disease

16:695:621 B1 1 Spring 2026

Cancer Cell Metabolism

16:695:622 B1 1 Spring 2026

Cellular Reprogramming in the Context of Development and Disease

16:695:623 B1 1 Spring 2026

Theory and Practice of Cryo-EM for Molecular Biosciences

16:695:624 B1 1 Spring 2026

How to Make a Good Egg: A Molecular Perspective

16:695:625 B1 1 Spring 2026

Regeneration - All Cut Up To Be

16:695:626 B2 1 Spring 2026

Transformation in Aging Research: From Molecular Insights to Lifespan Interventions

16:695:627 B2 1 Spring 2026

Cancer Epigenetics

16:695:628 B2 1 Spring 2026

The Origins of Molecular Medicine

16:695:629 B2 1 Spring 2026

Targeted Modulation of Cell States

16:695:630 B2 1 Spring 2026

Ubiquitin/Proteasome System in Health and Disease

16:695:631 B3 1 Spring 2026

Integrated Stress Response: A Paradigm for Translational Control

16:695:632 B3 1 Spring 2026

Chromosome Chaos Unleashed: Exploring Aneuploidy's Role in Cancer and Disease Dynamics

16:695:634 B3 1 Spring 2026

Genome Origami

16:695:635 B3 1 Spring 2026