Graduate Program in Cellular and Molecular Pharmacology

  • Jin, Shengkan (Victor)

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    • Shengkan (Victor) Jin
    • Associate Professor
    • Department: Department of Pharmacology
    • Phone: 1.7322354329
    • Email: jinsh@rwjms.rutgers.edu
    • Robert Wood Johnson Medical School
    • 675 Hoes Lane West, Room 549
    • Piscataway, NJ 08854
    • Key Words: Targeting mitochondria for treating metabolic diseases and cancer, and treating genetic diseases by a new precision gene editing technology
  • Kong, Tony Ah-Ng

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    • Ah-Ng Tony Kong
    • Distinguished Professor
    • Department: Department of Pharmaceutics
    • Phone: 1.8484456369
    • Email: kongt@pharmacy.rutgers.edu
    • Director of Graduate Program in Pharmaceutical Science
    • Glaxo Professor of Pharmaceutics
    • Rutgers University
    • Ernest Mario School of Pharmacy, Room 228
    • Piscataway, NJ 08854
    • Key Words: Dietary phytochemicals and cancer prevention; Nrf2-mediated redox signaling; epigenetics/epigenomics; pharmacokinetics (PK)/pharmacodynamics (PD)
  • Kwan, Kelvin

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    • Kelvin Kwan
    • Associate Professor
    • Department: Department of Cell Biology & Neuroscience
    • Phone: 1.8484451781
    • Email: kelvin.kwan@rutgers.edu
    • Rutgers University
    • W. M. Keck Center for Collaborative Neuroscience
    • Nelson Lab-D250
    • 604 Allison Road
    • Piscataway, NJ 08854
    • Key Words: Molecular basis of inner ear regeneration
    • Lab Site URL
  • Laskin, Jeffrey D.

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    • Jeffrey D. Laskin
    • Distinguished Professor
    • Department: Department of Environmental & Community Medicine
    • Phone: 1.8484450176
    • Email: jl1450@rwjms.rutgers.edu
    • Robert Wood Johnson Medical School
    • Environmental and Occupational Health Sciences Institute
    • 675 Hoes Lane
    • Piscataway, NJ 08854
    • Key Words: Cancer research, oncogene expression and growth factor mediated signal transduction, tyrosine kinases, immunobiology of inflammation, nitric oxide
    • News Items: Two Rutgers Professors Elected Senior Members of the National Academy of Inventors
  • Lattime, Edmund C

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    • Edmund C. Lattime
    • Professor
    • Department: Department of Surgery
    • Phone: 1.7322358588
    • Email: lattimec@cinj.rutgers.edu
    • Associate Director
    • Robert Wood Johnson Medical School
    • The Cancer Institute of New Jersey
    • 195 Little Albany Street
    • New Brunswick, N.J. 08901
    • Key Words: Tumor immunology, immune mechanisms, genetically-based vaccine strategies
    • Lab Site URL
  • Liu, Fang

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    • Fang Liu
    • Associate Professor
    • Department: Department of Chemical Biology
    • Phone: 1.8484459783
    • Email: fangliu@cabm.rutgers.edu
    • Rutgers University
    • CABM
    • 679 Hoes Lane
    • Piscataway, NJ 08854
    • Key Words: Signal transduction and gene regulation, growth and differentiation control
  • Lobel, Peter

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    • Peter Lobel
    • Professor
    • Department: Department of Biochemistry & Molecular Biology
    • Phone: 1.8484459831
    • Email: lobel@cabm.rutgers.edu
    • Robert Wood Johnson Medical School
    • CABM Room 204
    • 679 Hoes Lane
    • Piscataway, NJ 08854
    • Key Words: Hereditary neurodegenerative diseases, functional genomics, lysosomes, protein targeting
  • McKinnon, Randall D

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    • Randall D. McKinnon
    • Professor
    • Department: Department of Surgery
    • Phone: 1.7322354419
    • Email: mckinnon@rwjms.rutgers.edu
    • Robert Wood Johnson Medical School
    • 675 Hoes Lane
    • Piscataway, NJ 08854
    • Key Words: Developmental neurobiology, neuroncology, growth factors
  • Milstein, Aaron D

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    • Aaron D Milstein
    • Assistant Professor
    • Department: Department of Neuroscience & Cell Biology
    • Phone: 1.8484459854
    • Email: milstein@cabm.rutgers.edu
    • Rutgers University
    • CABM - 679 Hoes Lane
    • Room 238
    • Piscataway, NJ 08854
    • Key Words: Computational dissection of the neural circuit mechanisms of learning and memory in health and disease
  • Minden, Audrey

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    • Audrey Minden
    • Associate Professor
    • Department: Department of Chemical Biology
    • Phone: 1.8484455766
    • Email: aminden@pharmacy.rutgers.edu
    • Rutgers University
    • Lab for Cancer Research, Room 205
    • 164 Frelinghuysen Road
    • Piscataway, NJ 08854
    • Key Words: Cancer cell biology, signal transduction, mammalian development
  • Moghe, Prabhas V

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    • Prabhas V. Moghe
    • Distinguished Professor
    • Department: Departments of Biomedical, Chemical & Biochemical Engineering
    • Phone: 1.8484456591
    • Email: moghe@soe.rutgers.edu
    • Rutgers University
    • 98 Brett Road
    • Piscataway, NJ 08854
    • Key Words: Cellular Bioengineering (Liver, Skin), Cell-Interactive Biomaterials, Micro/Nanosystems Bioengineering
    • News Items: Rutgers’ Academic Chief Makes His Mark Through Innovation
  • Nanda, Vikas

  • Pilch, Daniel

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    • Daniel Pilch
    • Professor
    • Department: Department of Pharmacology
    • Phone: 1.7322353352
    • Email: pilchds@rwjms.rutgers.edu
    • Robert Wood Johnson Medical School
    • RWJMS. Room 422A
    • Piscataway, NJ 08854
    • Key Words: Targeting cell division proteins for the treatment of multidrug-resistant bacterial infections / Identifying new antibiotics and drug combinations against clinically important bacterial pathogens / Study bacterial cell division using a newly developed fluorescence-based technology
  • Pine, Sharon R

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    • Sharon R. Pine
    • Associate Professor
    • Department: Department of Pharmacology
    • Phone: 1.7322359629
    • Email: pinesr@cinj.rutgers.edu
    • Robert Wood Johnson Medical School
    • The Cancer Institute of New Jersey, Rm 3041
    • 195 Little Albany Street
    • New Brunswick, NJ 08903-268
    • Key Words: Lung cancer; cancer health disparities; preclinical studies; targeted therapy; Notch1; Sox9
    • Lab Site URL
  • Rasin, Mladen-Roko

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    • Mladen-Roko Rasin
    • Associate Professor
    • Department: Department of Neuroscience & Cell Biology
    • Phone: 1.7322354553
    • Email: rasinml@rwjms.rutgers.edu
    • Robert Wood Johnson Medical School, Room 343A
    • 475 Hoes Lane
    • Piscataway, NJ 08854
    • Key Words: Molecular and cellular mechanisms of neocortical circuit formation
  • Roth, Monica

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    • Monica Roth
    • Professor
    • Department: Department of Pharmacology
    • Phone: 1.7322355048
    • Email: roth@rwjms.rutgers.edu
    • Robert Wood Johnson Medical School, Room 636
    • 675 Hoes Lane
    • Piscataway, NJ 08855
    • Key Words: Retroviruses: integration, reverse transcriptase, envelope proteins, gene therapy, targeted entry, structural studies
  • Runnels, Loren

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    • Loren Runnels
    • Associate Professor
    • Department: Department of Pharmacology
    • Phone: 1.7322354593
    • Email: runnellw@rwjms.rutgers.edu
    • Robert Wood Johnson Medical School
    • Research Tower, Fourth Floor
    • 675 Hoes Lane West
    • Piscataway, NJ 08854
    • Key Words: Signal transduction, Live cell imaging, Confocal microscopy, Biochemistry, Electrophysiology
  • Ryazanov, Alexey G

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    • Alexey G. Ryazanov
    • Professor
    • Department: Department of Pharmacology
    • Phone: 1.7322355526
    • Email: ryazanag@rwjms.rutgers.edu
    • Robert Wood Johnson Medical School, Room 443
    • 675 Hoes Lane
    • Piscataway, NJ 08854
    • Key Words: Novel protein kinases and signal transduction
  • Sabaawy, Hatem

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    • Hatem Sabaawy
    • Associate Professor
    • Department: Department of Medicine
    • Phone: 1.7322358081
    • Email: sabaawhe@cinj.rutgers.edu
    • Robert Wood Johnson Medical School
    • The Cancer Institute of NJ, Room 4557
    • 95 Little Albany Street
    • New Brunswick, NJ 08901
    • Key Words: Stem cells, cell cycle regulation and organoids for drug discovery
    • Lab Site URL

    The research efforts in the Sabaawy laboratory is focused on studying normal stem cell development and cancer stem cells utilizing patient-derived cells, genome sequencing, tumor initiation models, 3D stem cell derived organoid cultures and humanized mouse models and xenografts for drug discovery. These studies aim to dissect normal stem cell developmental pathways, and how cancer stem cells divert from these regulatory pathways. One major pathway for research focus in the laboratory is the regulation of stem cell self-renewal by the polycomb gene BMI1 and cyclin dependent kinase inhibitors p15 (CDKN2b) and p16 (CDKN2a) regulating the cell cycle and senescence. Utilizing novel organoid cultures, CRISPR- and recombinase-mediated genome editing and drug modifiers together with transgenic and xenograft approaches; the laboratory is generating models for precision therapy of several cancers such as prostate cancer, glioblastomas and leukemias.

    A parallel research effort in the laboratory is to study human mesenchymal stem cell (MSC)-based therapy and transplantation in regenerative medicine. Cell therapy using stem cells for regeneration of a failing organ or injury repair is a promising approach. Dr. Sabaawy and his colleagues are collaborating on international trials for utilizing MSCs cell therapy for injury repair.

     

    Publications

  • Scotto, Kathleen

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    • Kathleen W. Scotto
    • Professor
    • Department: Department of Pharmacology
    • Phone: 1.7322354812
    • Email: kathleen.scotto@rutgers.edu
    • Dean
    • Robert Wood Johnson Medical School
    • The Cancer Institute of NJ, Room 4558
    • 195 Little Albany Street
    • New Brunswick, NJ 08901
    • Key Words: Regulation of expression of drug resistance genes in human tumors