Dr. Kaelber invents improved viral gene therapy vectors through structure-based engineering and discovers mechanisms of virus gene delivery through cutting-edge cryo-electron microscopy (cryoEM) methods, including in situ cryo-electron tomography. He is also interested in reconstructing the ancient evolutionary history of viruses and in methods development for cryoEM. In general, his lab focuses on leveraging structural and nanoimaging methods to open problems in virology, with particular focus on ssDNA and other small viruses. He also serves are director of the Rutgers CryoEM & Nanoimaging Facility and is the 3DEM Advisor to the RCSB Protein Data Bank.
Program Faculty
- Jason T. Kaelber
- Associate Research Professor
- Department: Institute for Quantitative Biomedicine
- Graduate Program(s): Biochemistry | Physiology and Integrative Biology
- Major Research Interest(s): Computational Biology, Nanobiology / nanotechnology, Structural Biology, Virology
- Research Techniques: Atomic or Electron microscopy, Biochemistry, Cell Biology, Cell culture, Protein Structure / Crystallography
- Research Organism(s): Cell lines, in vitro, Viruses
- Rotation Faculty
- Phone: 1.8484455302
- Email:
This email address is being protected from spambots. You need JavaScript enabled to view it. - Institute for Quantitative Biomedicine
- Center for Integrative Proteomics Research CIPR, Rm 010D
- 174 Frelinghuysen Road
- Piscataway, NJ 08854-8076
- Key Words: cryo-EM, virology, gene therapy, electron microscopy, nanoimaging