The Anthony Lab studies homeostatic responses to changes in nutrient supply and environmental stress. Our experiments aim to identify dietary components and cellular processes that prevent and treat serious diseases and promote healthspan. Over the years my group has published numerous high impact publications which delineate mechanisms of metabolic regulation and proteostasis control by diet, drugs, genetics and environmental stressors. Our discoveries span organ systems including endocrine, gastrointestinal, hepatobiliary, immune, lymphatic, muscular and the central nervous system. With respect to diet and nutrient supply, we study how amino acid insufficiency or imbalance alters tissue proteostasis in the whole animal. We use experimental models that alter amino acid availability and work to understand how altering the supply of amino acids, in total or individually, is sensed and communicated under different metabolic states. We also are interested in circadian and biological rhythms in metabolism, metabolic and molecular responses to cold stress and exercise, and the crosstalk between diet and physical activity.
Program Faculty
- Tracy Anthony
- Professor
- Department: Department of Nutritional Sciences
- Graduate Program(s): Biochemistry | Cell and Developmental Biology
- Major Research Interest(s): Cell stress / Cell death, Gene regulation, Metabolism / Nutrition, RNA / ribosome biology, Signaling
- Research Techniques: Biochemistry, Bioinformatics / Computational, Metabolomics, Proteomics, Transcriptomics
- Research Organism(s): Cell lines, in silico, Mice
- Phone: 1.8125682204
- Email:
This email address is being protected from spambots. You need JavaScript enabled to view it. - School of Environmental and Biological Sciences
- Foran Hall, Room 166
- 59 Dudley Road
- New Brunswick, NJ 08901-0231
- Key Words: Nutrient sensing and signaling in metabolism, proteostasis control during environmental stress
- Lab Site URL