Our lab seeks to define the molecular logic of CRISPR-Cas prokaryotic adaptive immunity, with a primary focus on RNA-targeting type VI CRISPR-Cas13 systems. This work addresses fundamental questions in microbial defense and RNA biology while offering significant translational potential, including CRISPR-based diagnostics, precise RNA knockdown strategies, and sequence-specific antimicrobials.
Program Faculty
- Ekaterina Semenova
- Assistant Research Professor
- Department: Waksman Institute of Microbiology
- Graduate Program(s): Microbiology & Molecular Genetics
- Major Research Interest(s): RNA / ribosome biology
- Research Techniques: Biochemistry, Genetics
- Research Organism(s): Bacteria, in vitro
- Rotation Faculty
- Phone: 1.8484456423
- Email:
This email address is being protected from spambots. You need JavaScript enabled to view it. - Waksman Institute of Microbiology, Room 3009B
- 190 Frelinghuysen Road
- Piscataway, NJ 08854-8020
- Key Words: CRISPR-Cas, prokaryotic adaptive immunity, RNA targeting, tRNA cleavage, HEPN nuclease, Cas13, antiphage defense
- Lab Site URL