Integrative Structural Cell Biology. Through an interdisciplinary research program, the Dai lab focuses on two main areas: intrinsically disordered proteins and membrane complexes, both of which pose unique and compelling challenges in structural and cellular biology. By utilizing advanced multimodal bioimaging techniques—including cryo-electron tomography (cryo-ET), correlative light and electron microscopy (CLEM), and cryo-focused ion beam milling (cryo-FIB)—we aim to unravel the complex networks of protein-protein and protein-lipid interactions within living cells to illuminate the intricate structure-function relationships that underpin biological processes in human health and disease.
Program Faculty
- Wei Dai
- Associate Professor
- Department: Department of Cell Biology and Neuroscience
- Graduate Program(s): Biochemistry | Cell and Developmental Biology
- Major Research Interest(s): Computational Biology, Drug Discovery, Neuroscience, Structural Biology
- Research Techniques: Atomic or Electron microscopy, Biochemistry, Biophysics, Cell Biology, Protein Structure / Crystallography
- Research Organism(s): Cell lines, in vitro, Yeast
- Phone: 1.8484456560
- Email:
This email address is being protected from spambots. You need JavaScript enabled to view it. - School of Arts and Sciences
- Division of Life Sciences
- Center for Integrative Proteomics Research CIPR, Room 208G
- 174 Frelinghuysen Road
- Piscataway, NJ 08854-8076
- Key Words: Structural Biology, Neuroscience, Cryo-electron Microscopy, Protein Aggregation and Transmission, Membrane Protein, Protein-drug Interactions
- Lab Site URL
- News Items: Scientists Discover Key Factors in How Some Algae Harness Solar Energy