The main focus of our group is to develop predictive models of transcriptional regulation by integrating large-scale datasets to shed light on regulatory processes that are condition-specific. In conjunction with high-throughput experimental techniques, we will leverage such models to identify functional variants and mechanisms of action driving disease. Specifically, we are interested in investigating early stages of neural development using a combination of genomic profiling, functional genomics and computational analysis.
Program Faculty
- Anat Kreimer
- Assistant Professor
- Department: Department of Biochemistry and Molecular Biology
- Graduate Program(s): Cell and Developmental Biology
- Major Research Interest(s): Computational Biology, Disease genetics, Epigenetics/ Chromatin, Gene regulation, Neuroscience
- Research Techniques: Bioinformatics / Computational, Cell Biology, Genetics, Genomics, Transcriptomics
- Research Organism(s): Cell lines, Humans
- Robert Wood Johnson Medical School
- Center for Advanced Biotechnology & Medicine CABM
- 679 Hoes Lane West
- Piscataway, NJ 08854-8021
- Key Words: Computational Biology, Gene regulation, Functional genomics, Neural development, Human variation