Graduate Program in Physiology & Integrative Biology

Graduate Program in Physiology & Integrative Biology

  • Buettner, Christoph

    • Christoph Buettner
    • Christoph Buettner
    • Professor
    • Department: Department of Medicine
    • Graduate Program(s): Cellular & Molecular Pharmacology | Physiology & Integrative Biology
    • Major Research Interest(s): Aging, Endocrinology, Metabolism / Nutrition, Microbiome, Signaling
    • Research Techniques: Clinical trials, Metabolomics
    • Research Organism(s): Humans, Mice
    • Phone: 1.7322357219
    • Robert Wood Johnson Medical School
    • Clinical Academic Building CAB, Room 7204
    • 125 Paterson Street
    • New Brunswick, NJ 08901-1977
    • Lab Site URL
  • Bunting, Samuel

    • Samuel Bunting
    • Samuel F. Bunting
    • Associate Professor
    • Department: Department of Molecular Biology and Biochemistry
    • Graduate Program(s): Biochemistry | Cell & Developmental Biology | Microbiology & Molecular Genetics | Physiology & Integrative Biology
    • Major Research Interest(s): Cancer Biology, Cell division / Cell cycle, Chromosome Biology, DNA replication and repair
    • Research Techniques: Biochemistry, Cell Biology, Cell culture, Genetic engineering, Genetics
    • Research Organism(s): Humans, in vitro, Mice
    • Phone: 1.8484459894
    • Center for Advanced Biotechnology and Medicine CABM, Room 337
    • 679 Hoes Lane West
    • Piscataway, NJ 08854
    • Key Words: Cell survival and DNA repair in mammals
  • De, Subhajyoti

    • Subhajyoti De
    • Subhajyoti De
    • Associate Professor
    • Department: Department of Pathology and Laboratory Medicine
    • Graduate Program(s): Cellular & Molecular Pharmacology | Physiology & Integrative Biology
    • Major Research Interest(s): Cancer Biology, Computational Biology, Evolution, Microbiome
    • Research Techniques: Bioinformatics / Computational, Genomics, Single Cell RNA Techniques
    • Research Organism(s): Cell lines, Humans
    • Phone: 1.7322358558
    • Robert Wood Johnson Medical School
    • Cancer Institute of New Jersey CINJ, Room 4558
    • 195 Little Albany Street
    • New Brunswick, NJ 08901-1998
    • Key Words: Cancer genomics, genome evolution, algorithms, systems biology, precision medicine
    • Lab Site URL
    • News Items: Microorganisms in Tumors May Help Identify New Approaches for Treating Pancreatic Cancer
  • Fan, Huizhou

    • Huizhou Fan
    • Huizhou Fan
    • Professor
    • Department: Department of Pharmacology
    • Graduate Program(s): Cell & Developmental Biology | Microbiology & Molecular Genetics | Physiology & Integrative Biology
    • Major Research Interest(s): Gene regulation
    • Research Techniques: Biochemistry, Bioinformatics / Computational, Cell culture, Genetic engineering, Transcriptomics
    • Research Organism(s): Bacteria, Cell lines, in silico, Mice
    • Phone: 1.7322354607
    • Robert Wood Johnson Medical School
    • RWJMS Research Tower, Room 400
    • 675 Hoes Lane West
    • Piscataway, NJ 08854-5635
    • Key Words: Chlamydia, sexually transmitted infections, gene expression, transcriptomics
  • Grant, Barth

    • Barth Grant
    • Barth Grant
    • Distinguished Professor
    • Department: Department of Molecular Biology and Biochemistry
    • Graduate Program(s): Biochemistry | Cell & Developmental Biology | Microbiology & Molecular Genetics | Physiology & Integrative Biology
    • Research Organism(s): C. elegans
    • Phone: 1.8484457339
    • School of Arts and Sciences
    • Nelson Biology Laboratories, Room A231
    • 604 Allison Road
    • Piscataway, NJ 08854
    • Key Words: Receptor trafficking and signaling, genetics, cell biology, membranes, endocytosis, C. elegans, functional genomics
    • Lab Site URL
  • Jacinto, Estela

    • Estela Jacinto
    • Estela Jacinto
    • Professor
    • Department: Department of Biochemistry and Molecular Biology
    • Graduate Program(s): Cell & Developmental Biology | Microbiology & Molecular Genetics | Physiology & Integrative Biology
    • Major Research Interest(s): Aging, Cancer Biology, Immunology, Metabolism / Nutrition, Signaling
    • Research Techniques: Biochemistry, Cell Biology, Cell culture, Metabolomics, Proteomics
    • Research Organism(s): Cell lines, Mice
    • Rotation Faculty
    • Phone: 1.7322354476
    • Robert Wood Johnson Medical School
    • RWJMS Research Building & School of Public Health, Room 260
    • 683 Hoes Lane West
    • Piscataway, NJ 08854-8021
    • Key Words: T lymphocytes, metabolism, cancer, signal transduction, glycosylation
    • Lab Site URL
  • Kaelber, Jason

    • Jason T. Kaelber
    • Jason T. Kaelber
    • Associate Research Professor
    • Department: Institute for Quantitative Biomedicine
    • Graduate Program(s): Biochemistry | Physiology & Integrative Biology
    • Major Research Interest(s): Computational Biology, Nanobiology / nanotechnology, Structural Biology, Virology
    • Research Techniques: Atomic or Electron microscopy, Biochemistry, Cell Biology, Cell culture, Protein Structure / Crystallography
    • Research Organism(s): Cell lines, in vitro, Viruses
    • Phone: 1.8484455302
    • Institute for Quantitative Biomedicine
    • Center for Integrative Proteomics Research CIPR, Rm 010D
    • 174 Frelinghuysen Road
    • Piscataway, NJ 08854-8076
    • Key Words: cryo-EM, virology, gene therapy, electron microscopy, nanoimaging

    Dr. Kaelber invents improved viral gene therapy vectors through structure-based engineering and discovers mechanisms of virus gene delivery through cutting-edge cryo-electron microscopy (cryoEM) methods, including in situ cryo-electron tomography. He is also interested in reconstructing the ancient evolutionary history of viruses and in methods development for cryoEM. In general, his lab focuses on leveraging structural and nanoimaging methods to open problems in virology, with particular focus on ssDNA and other small viruses. He also serves are director of the Rutgers CryoEM & Nanoimaging Facility and is the 3DEM Advisor to the RCSB Protein Data Bank.

    Publications

    NCBI Bibliography

  • Merrill, Gary F.

    • Gary F. Merrill
    • Gary F. Merrill
    • Professor
    • Department: Department of Cell Biology and Neuroscience
    • Graduate Program(s): Cell & Developmental Biology | Physiology & Integrative Biology
    • Major Research Interest(s): Aging, Drug Discovery, Metabolism / Nutrition
    • Research Techniques: Atomic or Electron microscopy, Biochemistry, Biophysics, Imaging
    • Research Organism(s): Humans, in vitro
    • Phone: 1.8484452320
    • School of Arts and Sciences
    • Division of Life Sciences
    • Nelson Biological Laboratories, Room B222
    • 604 Allison Road
    • Piscataway, NJ 08854-8000
    • Key Words: acetaminophen and cytoprotection; caffeine and the cardiovascular system in young adults
  • Pang, Zhiping

  • Sesti, Federico

    • Federico Sesti
    • Federico Sesti
    • Professor
    • Department: Department of Neuroscience and Cell Biology
    • Graduate Program(s): Cellular & Molecular Pharmacology | Physiology & Integrative Biology
    • Major Research Interest(s): Aging, Cytoskeleton, Neurological disease, Neuroscience, Signaling
    • Research Techniques: Biochemistry, Cell Biology, Cell culture, Fluorescent and super resolution microscopy, Imaging
    • Research Organism(s): Cell lines, in vitro, Mice
    • Rotation Faculty
    • Phone: 1.9084429458
    • Robert Wood Johnson Medical School
    • RWJMS Research Building and School of Public Health, Room 156
    • 683 Hoes Lane West
    • Piscataway, NJ 08854-8021
    • Key Words: Physiology, structure and function of potassium channels, role of potassium channels in causing disease
    • Lab Site URL
  • Shah, Ankit

    • Ankit Shah
    • Ankit Shah
    • Assistant Professor
    • Department: Department of Medicine
    • Graduate Program(s): Physiology & Integrative Biology
    • Major Research Interest(s): Endocrinology, Metabolism / Nutrition, Pathogenesis
    • Research Techniques: Biochemistry, Clinical trials, Metabolomics
    • Research Organism(s): Humans, in vitro
    • Phone: 1.7322356337
    • Robert Wood Johnson Medical School
    • Clinical Academic Building CAB, Room 7203
    • 125 Paterson Street
    • New Brunswick, NJ 08901-1977
    • Key Words: metabolism, mass spectrometry, endocrinology, isotope tracer
  • Watford, Malcolm

    • Malcolm Watford
    • Malcolm Watford
    • Professor
    • Department: Department of Nutritional Sciences
    • Graduate Program(s): Physiology & Integrative Biology
    • Phone: 1.8489326263
    • School of Environmental and Biological Sciences
    • Foran Hall, Room 179
    • 59 Dudley Road
    • New Brunswick, NJ 08901-8520
    • Key Words: The role of amino acids as substrates for gluconeogenesis and urea synthesis
    • Lab Site URL
  • Welsh, William J

  • Xiao, Shuo

    • Shuo Xiao
    • Shuo Xiao
    • Associate Professor
    • Department: Department of Pharmacology and Toxicology
    • Graduate Program(s): Physiology & Integrative Biology
    • Major Research Interest(s): Drug Discovery, Endocrinology, Reproduction and Gametogenesis, Stem Cells, Regeneration, and Tissue Injury
    • Research Techniques: Cell Biology, Cell culture, Single Cell RNA Techniques, Transcriptomics
    • Research Organism(s): Humans, in vitro
    • Phone: 1.8484453729
    • Ernest Mario School of Pharmacy
    • Environmental & Occupational Health Sciences Institute EOHSI
    • 170 Frelinghuysen Road
    • Piscataway, NJ 08854-8020
    • Key Words: Women's reproductive health, organ-on-chip, toxicology, fertility preservation
    • Lab Site URL

    Dr. Xiao and his team focus on multiple research interests in female reproductive biology and toxicology, including (1) ovarian impacts of environmental contaminants and clinical drugs; (2) drug development of non-hormonal female contraception and fertoprotectant, and (3) engineering female reproduction-on-chip. These projects are supported by NIEHS, NICHD, DOD, and Bill & Melinda Gates Foundation.

    Publications

    NCBI Bibliography

  • Yang, Qi

    • Qi Yang
    • Qi Yang
    • Associate Professor
    • Department: Department of Pediatrics
    • Graduate Program(s): Cell & Developmental Biology | Physiology & Integrative Biology
    • Major Research Interest(s): Aging, Immunology, Neuroscience, Pathogenesis
    • Research Techniques: Bioinformatics / Computational, Cell Biology, Single Cell RNA Techniques
    • Research Organism(s): Humans, Mice
    • Rotation Faculty
    • Phone: 1.7322354501
    • Robert Wood Johnson Medical School
    • Child Health Institute of New Jersey CHI
    • 89 French Street
    • New Brunswick, NJ 08901-1935
    • Key Words: neuroimmunology, immune cell-neuron interaction
    • Lab Site URL

    The research in the Yang laboratory focuses on the most current topics in the intersecting fields of immunology and neuroscience. Recent research has shed new light on the close interaction between the immune system and the brain, challenging the traditional notion of the immune privilege of the brain. At the forefront of this exploration, we are committed to advancing our understanding of the role played by brain-associated lymphocytes in regulating brain barrier integrity, neuroinflammation, and cognition.

    Our work, featured in Nature Immunology (2022) and the Journal of Experimental Medicine (2020), focuses on unraveling the inflammatory mechanisms underlying Alzheimer’s disease and vascular dementia. We welcome students with a keen interest in immunology or neuroscience to join us in delving into this exciting field.

    Our ongoing projects cover a diverse array of areas:

    • Investigating the role of tissue-resident lymphocytes in maintaining the integrity of brain barriers and their impact on the brain's physiological function.
    • Exploring the interactions between brain-infiltrating immune cells, glia cells, and neurons, particularly in the context of aging, Alzheimer’s disease, and vascular dementia.
    • Profiling the spatial and single-cell atlas of immune cells in the brain across various disease states.

    Publications

  • Zhang, Huaye

    • Huaye Zhang
    • Huaye Zhang
    • Professor
    • Department: Department of Neuroscience and Cell Biology
    • Graduate Program(s): Cell & Developmental Biology | Cellular & Molecular Pharmacology
    • Major Research Interest(s): Learning / memory, Neurological disease, Neuroscience, Signaling
    • Research Techniques: Biochemistry, Cell Biology, Cell culture, Fluorescent and super resolution microscopy, Genetic engineering
    • Research Organism(s): Cell lines, Mice
    • Phone: 1.7322353433
    • Robert Wood Johnson Medical School
    • RWJMS Research Tower, Room 304
    • 675 Hoes Lane West
    • Piscataway, NJ 08854-8021
    • Key Words: cell polarity, dendritic spines, synaptic plasticity, membrane trafficking, cytoskeleton, autism, Alzheimer's disease, learning and memory
    • Lab Site URL