Graduate Program in Biochemistry
Graduate Program in Biochemistry
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Anthony, Tracy
- Tracy Anthony
- Professor
- Department: Department of Nutritional Sciences
- Phone: 1.8489326331
- Email: tracy.anthony@rutgers.edu
- Rutgers University
- School of Environmental & Biological Sciences
- Institute for Food, Nutrition & Health
- 61 Dudley Rd
- New Brunswick, NJ 08901-0231
- Key Words: Protein and amino acid metabolism; adaptation to cell stress by eIF2 and mTOR pathways; nutrition and exercise
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Arnold, Edward
- Edward Arnold
- Distinguished Professor
- Department: Department of Chemistry & Chemical Biology
- Program(s): Biochemistry Graduate Program, Microbiology and Molecular Genetics Graduate Program
- Phone: 1.8484459777
- Email: arnold@cabm.rutgers.edu
- Rutgers University
- Center for Advanced Biotechnology & Medicine
- 679 Hoes Lane
- Piscataway, NJ 08854
- Key Words: HIV, AIDS, drugs, vaccines, crystallography, structural biology
- News Items: How to Stop the Next Pandemic Before It Starts, Research Reveals Structure of a Human Endogenous Reverse Transcriptase , Understanding the Structure of HIV Protein May Lead to Novel Treatments
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Axelrod, David
- David Axelrod
- Professor
- Department: Genetics
- Phone: 1.8484452011
- Email: axelrod@dls.rutgers.edu
- Rutgers University
- Nelson Biology Labs. Rm B341
- 604 Allison Rd
- Piscataway, NJ 08854
- Key Words: Cell and molecular oncology, breast cancer, colon cancer
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Barber, Annika
- Annika F. Barber
- Assistant Professor
- Department: Department of Molecular Biology & Biochemistry
- Email: annika.barber@waksman.rutgers.edu
- Rutgers University
- Waksman Institute. Room 234
- 190 Frelinghuysen Rd Piscataway, NJ 08854
- Piscataway. NJ 08854-0759
- Key Words: Neural signal integration in Drosophila behavioral circuits
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Barr, Maureen
- Maureen M. Barr
- Distinguished Professor
- Department: Department of Genetics
- Phone: 1.8484451639
- Email: mmbarr@hginj.rutgers.edu
- Rutgers University
- Life Sciences Building, Room 324
- Piscataway. NJ 08854
- Key Words: Cilia cell biology, sensory behaviors, and modeling human genetic diseases in C. elegans
- Lab Site URL
- News Items: Once Called Cellular Debris, Tiny Bubbles May Play Key Role in Understanding, Treating Diseases
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Baum, Jean
- Jean Baum
- Distinguished Professor
- Department: Department of Chemistry
- Phone: 1.8484455666
- Email: baum@chem.rutgers.edu
- Rutgers University
- Proteomics
- 174 Frelinghuysen Rd.
- Piscataway, NJ 08854
- Key Words: NMR, protein folding, molecular recognition
- Lab Site URL
- News Items: Researchers Receive “High Risk-High Payoff” Grant From NSF
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Boison, Detlev
- Detlev Boison
- Professor
- Department: Department of Neurosurgery
- Phone: 1.7322356373
- Email: detlev.boison@rutgers.edu
- Rutgers University
- Robert Wood Johnson Medical School
- Research/School of Public Health
- 683 Hoes Lane West
- Piscataway, NJ 08854
- Key Words: Epigenetics of epilepsy, traumatic brain injury, comorbidities in neurology, role of adenosine in cancer, metabolic therapies
- Lab Site URL
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Boyd, Jeff
- Jeff Boyd
- Associate Professor
- Department: Department of Biochemistry and Microbiology
- Program(s): Biochemistry Graduate Program, Microbiology and Molecular Genetics Graduate Program
- Major Research Interest(s): Biochemistry, Microbiology, Molecular Genetics, Physiology
- Phone: 1.8489325604
- Email: jeffboyd@sebs.rutgers.edu
- Rutgers University
- School of Environmental & Biological Sciences
- Lipman Hall, Room 329
- 76 Lipman Drive
- New Brunswick, NJ 08901-0231
- Key Words: Bacterial pathogenesis, antibiotic resistance, metal ion homeostasis, molecular microbiology, oxidative stress, environmental sensing
- News Items: Scientists Discover Genes that Help Harmful Bacteria Thwart Treatment
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Breslauer, Kenneth J
- Kenneth J. Breslauer
- Professor
- Department: Department of Chemistry & Chemical Biology
- Phone: 1.8484453956
- Email: kjbdna@rci.rutgers.edu
- Linus C. Pauling Distinguished Professor
- Dean, Life Sciences
- Vice President, Health Science Partnerships
- Wright Labs
- Piscataway, NJ 08854
- Key Words: Drug-DNA interactions, DNA polymorphism, macroscopic and microscopic characterizations of inter- and intramolecular forces, biothermodynamics, DNA lesions and mechanisms of mutagenesis and repair, ligand-biopolymer recognition, rational drug design, DNA-based diagnostics and therapeutics
- News Items: Genetic Code Evolution and Darwin’s Evolution Theory Should Consider DNA an ‘Energy Code’
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Brewer, Gary
- Gary Brewer
- Professor
- Department: Department of Biochemistry & Molecular Biology
- Phone: 1.7322353473
- Email: brewerga@rutgers.edu
- Robert Wood Johnson Medical School
- 675 Hoes Lane
- Piscataway, NJ 08854-5635
- Key Words: Post-transcriptional control of gene expression in cancer, immune responses, and congestive heart failure
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Brill, Steven J
- Steven J. Brill
- Professor
- Department: Department of Molecular Biology and Biochemistry
- Phone: 1.8484459863
- Email: brill@cabm.rutgers.edu
- Rutgers University
- CABM - 679 Hoes Lane
- Piscataway, NJ 08854
- Key Words: DNA replication, DNA repair, DNA helicase, genetic analysis, genome stability, protein purification, yeast
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Bunting, Samuel F
- Samuel F. Bunting
- Associate Professor
- Department: Department of Molecular Biology and Biochemistry
- Phone: 1.8484459894
- Email: bunting@cabm.rutgers.edu
- Rutgers University
- CABM Room 337
- 679 Hoes Lane
- Piscataway, NJ 08854
- Key Words: Cell survival and DNA repair in mammals
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Carman, George M
- George M. Carman
- Board of Governors Professor
- Department: Department of Food Science
- Phone: 1.8489320267
- Email: gcarman@rutgers.edu
- Center for Lipid Resesarch
- School of Biological and Environmental Sciences
- Institute of Food, Nutrition, and Health, Room 12
- 61 Dudley Road
- New Brunswick, NJ 08901-8520
- Key Words: Regulation of Phospholipid Metabolism/Signaling in Yeast
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Chada, Kiran
- Kiran Chada
- Professor
- Department: Department of Biochemistry & Molecular Biology
- Phone: 1.7322354026
- Email: chada@rwjms.rutgers.edu
- Robert Wood Johnson Medical School
- 675 Hoes Lane
- Piscataway, NJ 08854
- Key Words: Mammalian genetics. human diseases, developmental biology, obesity cancer
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Chen, Suzie
- Suzie Chen
- Professor
- Department: Department of Chemical Biology
- Program(s): Biochemistry Graduate Program, Cell and Developmental Biology Graduate Program, Microbiology and Molecular Genetics Graduate Program
- Phone: 1.8484457243
- Email: suziec@pharmacy.rutgers.edu
- Rutgers University
- Lab for Cancer Research. Room 213
- 164 Frelinghuysen Road
- Piscataway, NJ 08854
- Key Words: Mouse model of melanoma, regulation of cell signaling by G-protein-coupled receptor
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Dai, Wei
- Wei Dai
- Assistant Professor
- Department: Department of Cell Biology & Neuroscience
- Program(s): Biochemistry Graduate Program, Cell and Developmental Biology Graduate Program
- Phone: 1.8484456560
- Email: wd157@dls.rutgers.edu
- Rutgers University
- Center for Advanced Proteomics
- 174 Frelinghuysen Rd.
- Piscataway, NJ 08854
- Key Words: Structural biology of neurodegenerative diseases by cryo-electron tomography
- News Items: Scientists Discover Key Factors in How Some Algae Harness Solar Energy
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Demokritou, Philip
- Philip Demoktritou
- Professor
- Department: Division of Environmental & Population Health Biosciences
- Phone: 1.8484450155
- Email: philip.demokritou@rutgers.edu
- Henry Rutgers Chair and Professor in Nanoscience and Environmental Bioengineering
- Environmental & Occupational Health Sciences Institute
- 170 Frelinghuysen Road
- Piscataway, NJ 08854
- Key Words: nanobiology, nanotoxicology; environmental pollutants
- News Items: Combatting Climate Change’s Effects With Artificial Intelligence, Nanotechnology and More by a Hair
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Dismukes, G. Charles
- G. Charles Dismukes
- Distinguished Professor
- Department: Department of Chemistry & Chemical Biology
- Phone: 1.8484451489
- Email: dismukes@chem.rutgers.edu
- Rutgers University
- Waksman Institute. Room 1014A
- Piscataway, NJ 08854-0759
- Key Words: Microbial metabolism and renewable energy production
- Lab Site URL
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Dougherty, Joseph P
- Joseph Dougherty
- Professor
- Department: Department of Pharmacology
- Program(s): Biochemistry Graduate Program, Microbiology and Molecular Genetics Graduate Program
- Phone: 1.7322354588
- Email: doughejp@rwjms.rutgers.edu
- Robert Wood Johnson Medical School, Room 811
- Piscataway, NJ 08854
- Key Words: HIV-1 replication. gene therapy and retroviral vectors
Research in our laboratory centers upon studying HIV-1 replication and upon the design and use of retroviral vectors for somatic cell gene therapy involving cells of the lymphoid lineage.
Our recent HIV-1 studies have focused upon investigating HIV-1 reverse transcription and recombination. DNA primer strand transfers are essential for HIV-1 replication, and recombination influences the rapid evolution of HIV- 1. The accepted mechanism of retroviral reverse transcription proposes that two primer strand transfers occur during replication. Given the diploid nature of the retroviral virion, the question arises concerning the nature of these primer strand transfers, namely, whether they are intra- or intermolecular. A system was developed to examine the nature of primer transfer events during HIV-1 replication. Both intra- and intermolecular primer transfer were observed. and occurred with similar frequencies during minus strand synthesis. Plus-strand primer transfer was primarily intramolecular. A high rate of homologous recombination occurred during minus-strand DNA synthesis. Recombination occurred at a rate of 3 cross-overs per genome per replication cycle. These results suggest that both viral genomic RNAs serve as templates during HIV-1 reverse transcription and that primer strand transfers as well as recombination contribute to the rapid genetic variation of HIV-1.
Primary lymphocytes play a key role in immune surveillance and regulation. Moreover, they are long-lived and easy to obtain. Because of these considerations, they are potentially important targets for somatic cell gene therapy. Using retroviral vectors, we have developed efficient gene transfer procedures for introducing genes into primary lymphocytes. The procedures do not perturb the primary lymphocytes, since after transplantation into recipient hosts, they home to the appropriate lymphoid organs, persist for long periods of time, and express the transferred genes at significant levels. Thus, we are in a position to genetically manipulate lymphocytes and are using this technology to develop procedures for treating autoimmune diseases, such as multiple sclerosis.
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Driscoll, Monica
- Monica Driscoll
- Professor
- Department: Department of Molecular Biology and Biochemistry
- Phone: 1.8484457182
- Email: driscoll@dls.rutgers.edu
- Rutgers University
- Nelson Biological Labs. Room A232
- Piscataway, NJ 08854
- Key Words: Developmental neurogenetics. molecular genetics of neuronal cell death. mechanosensory transduction in touch and feeling. molecular mechanisms of aging
- News Items: Research Team Studying Aging and Disease Adapts During Pandemic
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